| InjectinIn Vivo siRNA Delivery Kit
Injectin In Vivo siRNA Delivery Kit contains a new lipid-based formulation which enables the delivery of siRNA into living organisms. Injectin reagent has been especially developed for local and systemic siRNA administrations in mouse. Due to it's high efficiency and it's stability, Injectin reagent is able to maintain in vivo silencing of gene expression for a very long time, without the need of multiple injection repeats.
Main advantagesHigh siRNA Delivery EfficiencyLocal and Systemic Administrations No Need for Multiple Injection Repeats
Prevent siRNA Degradation from RNaseNo Detectable Inflammatory Response
Not Cytotoxic |  | 
10 µg of a luciferase siRNA were directly injected into a 100 mm3 mouse tumor 4T1 expressing luciferase by using 10 µL of Injectin reagent. The same experiment was performed by using other in vivo siRNA delivery reagents (X, Y and Z) according to manufacturer's protocols. After 8 days, tumors were excised and lysed in a protease inhibitor solution. Luciferase activities were measured with a luminometer. All data were corrected by protein concentration assays. |
IJ100
| 100 µL Injectin reagent / 100 µL glucose buffer Suitable for 10 intratumoral injections | | IJ500
| 500 µL Injectin reagent / 500 µL glucose buffer Suitable for 10 intravenous injections | |
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